Toelichting op glucosamine

Glucosamine (wetenschappelijke naam: 2-Amino-2-deoxyglucose)

Kraakbeen bestaat uit collageen, elastine en een matrix van lange suiker-eiwitmolecules genaamd proteoglycanen en glycosaminoglycanen. Deze glycosaminoglycanen zijn uitermate belangrijk voor het vermogen van kraakbeen te fungeren als een schokdemper; door hun sterke waterabsorptie maken ze kraakbeen gelachtig en veerkrachtig. Artrose wordt gekenmerkt door een progressieve degeneratie van de kraakbeenglycosaminoglycanen. Glucosamine vergemakkelijkt de synthese van glycosaminoglycanen; het aanvullen van de beschikbaarheid van glucosamine vertraagt daarom de degeneratie van het kraakbeen. Glucosamine kan ook ontstekingen verminderen en kraakbeen beschermen tegen schade veroorzaakt door NSAID's, corticosteroïden.

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