Toelichting op glucosamine

Glucosamine (wetenschappelijke naam: 2-Amino-2-deoxyglucose)

 

Kraakbeen bestaat uit collageen, elastine en een matrix van lange suiker-eiwitmolecules genaamd proteoglycanen en glycosaminoglycanen. Deze glycosaminoglycanen zijn uitermate belangrijk voor het vermogen van kraakbeen te fungeren als een schokdemper; door hun sterke waterabsorptie maken ze kraakbeen gelachtig en veerkrachtig. Artrose wordt gekenmerkt door een progressieve degeneratie van de kraakbeenglycosaminoglycanen. Glucosamine vergemakkelijkt de synthese van glycosaminoglycanen; het aanvullen van de beschikbaarheid van glucosamine vertraagt daarom de degeneratie van het kraakbeen. Glucosamine kan ook ontstekingen verminderen en kraakbeen beschermen tegen schade veroorzaakt door NSAID's, corticosteroïden.


Glucosamine CMN Plus

€ 17,50


 

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24.   Ali AA, Lewis SM, Badgley HL, Allaben WT, Leakey JE. Oral glucosamine increases expression of transforming growth factor beta 1 (TGF-beta 1) and connective tissue growth factor (CTGF) mRNA in rat cartilage and kidney: implications for human efficacy and toxicity. Arch Biochem Biophys. 2011 Jun 1;510(1):11-8.